Azido-PEG4-Amido-Tris is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Bromo-PEG5-bromide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
endo-BCN-PEG3-NH2 is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Thiol-PEG3-acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Azido-PEG8-C-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Mal-PEG5-C2-NH2 hydrochloride is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Thalidomide-O-C4-NH2 is a synthesized E3 ligase ligand-linker conjugate that incorporates the Thalidomide based cereblon ligand and a linker used in PROTAC technology[1].
Acid-PEG3-mono-methyl ester is an alkyl/ether-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Propargyl-PEG4-CH2COOH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Benzyl-PEG4-MS is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Azido-PEG8-PFP ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Propynyl-PEG1-Ac is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
PROTAC MDM2 Degrader-4 is a MDM2 degrader based on PROTAC technology. PROTAC MDM2 Degrader-4 composes of a potent MDM2 inhibitor, linker, and the MDM2 ligand for E3 ubiquitin ligase[1].
Bis-PEG3-PFP ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Propenyl-PEG3-Propenyl is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
PROTAC Linker 15 is a PROTAC linker, which refers to the alkyl/ether composition. PROTAC Linker 15 can be used in the synthesis of a series of PROTACs. PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
N-DBCO-N-bis(PEG2-C2-acid) is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Propargyl-PEG4-CH2-acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
N-(Azido-PEG4)-N-bis(PEG4-t-butyl ester) is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
NH-bis-PEG3 is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Pomalidomide-5-C8-NH2 hydrochloride is the Pomalidomide (HY-10984)-based cereblon (CRBN) ligand used in the recruitment of CRBN protein. Pomalidomide-5-C8-NH2 hydrochloride can be connected to the ligand for protein by a linker to form PROTAC[1].
(R,S,S)-VH032 is Ligand for E3 Ligase used in the synthesis of PROTACs. VH032 is a VHL ligand and VHL/HIF-1α interaction inhibitor that recruits von Hippel-Lindau (VHL) proteins. (R,S,S)-VH032 synthesizes the tau-targeting small molecule PROTAC C004019 (HY-138669)[1].
N-Ethyl-N-methylpropionamide-PEG1-Br is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Pyrroline-5-carboxylate is an alkyl/ether-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Azide-PEG8-alcohol is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
m-PEG10-CH2COOH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Mal-NH-PEG2-CH2CH2COOPFP ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Fluorescein-PEG3-NH-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Propargyl-PEG2-Tos is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Propargyl-PEG2-amine is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Propargyl-PEG2-amine is a PEG-based PROTAC linker can be used in the synthesis of PROTACs[1][2].