Diphenylmethylene-glycine benzyl ester is a Glycine (HY-Y0966) derivative[1].
N-(tert-Butoxycarbonyl)-D-threonine Methyl Ester is a threonine derivative[1].
Febuxostat impurity 8 is an impurity of Febuxostat. Febuxostat is selective xanthine oxidase inhibitor with a Ki of 0.6 nM[1].
L-Threonine-13C4,d5,15N is the deuterium, 13C-, and 15-labeled L-Threonine. L-Threonine is a natural amino acid, can be produced by microbial fermentation, and is used in food, medicine, or feed[1].
Biotin NHS is an amino reactive biotin reagent used in the preparation of biotinylated surfaces or polypeptides.
m-TMPyP tetrachloride is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
(2S,3R)-2,3,4-Trihydroxybutanal-13C-1 is the 13C labeled (2S,3R)-2,3,4-Trihydroxybutanal[1].
Boc-Gly-Lys-Arg-AMC is a polypeptide that can be found by peptide screening. Peptide screening is a research tool that pools active peptides primarily by immunoassay. Peptide screening can be used for protein interaction, functional analysis, epitope screening, especially in the field of agent research and development[1].
H-Pro-Pro-Pro-OH is a triproline.
5’(R)-C-Methyladenosine is a purine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].
Scandine is a alkaloid compound isolated from the twigs and leaves of Melodinus suaveolens[1].
2,3-Dehydrosilybin B is an enantiomer formed by the oxidation of the natural flavonolignans silybin A[1].
DOTMA, as a tetra-methylated DOTA analogue, is a cationic lipid and can be used as a non-viral vector for gene therapy. It has been used as a component in liposomes that can be used to encapsulate siRNA, microRNAs, and oligonucleotides and for gene transfection in vitro. It exhibits effective in vitro and in vivo gene transfection. DOTMA induces a positive charge on the liposomes and thus promotes efficient liposome- cell membrane interaction[1][2][3].
β-Tomatine is a breakdown product of a-tomatine and a less fungitoxic compound. β-Tomatine can suppress plant defense responses[1].
H-His-Asp-OH is adipeptide.
Diversoside is a natural product that can be isolated from Notopterygium forbesii[1].
3’-Azido-3’-deoxy-5-methyl-beta-L-uridine is a purine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].
Encecalin is a natural benzofuran compound[1].
2-Naphthol-d7 is the deuterium labeled 2-Naphthol[1]. 2-Naphthol is a metabolite of naphthalene, catalyzed by cytochrome P450 (CYP) isozymes (CYP 1A1, CYP 1A2, CYP 2A1, CYP 2E1 and CYP 2F2)[2].
DSPE-PEG-Maleimide has DSPE phospholipid and maleimide to prepare nanostructured lipid carrier. DSPE-PEG-Maleimide extends blood circulation time and higher stability for encapsulated drugs[1][2].
Cyclopropyl-1 Methyl-Ketone-d4 is the deuterium labeled Cyclopropyl methyl ketone[1].
Noroxyhydrastinine (compound 1) is an alkaloid. Noroxyhydrastinine can be isolated from the ethanolic extract of the roots of Thalictrum angustifolium[1].
ST271 is a potent inhibitor of protein tyrosine kinase (PTK).
Methyl 2-(cyclopentylamino)acetate hydrochloride is a Glycine (HY-Y0966) derivative[1].
N-Methyl-N’-nitrosopiperazine-d4 is the deuterium labeled N-Methyl-N’-nitrosopiperazine[1].
L-Arginine is the nitrogen donor for synthesis of nitric oxide, a potent vasodilator that is deficient during times of sickle cell crisis.Target: OthersL-Arginine is an α-amino acid. It was first isolated in 1886. The L-form is one of the 20 most common natural amino acids. At the level of molecular genetics, in the structure of the messenger ribonucleic acid mRNA, CGU, CGC, CGA, CGG, AGA, and AGG, are the triplets of nucleotide bases or codons that code for arginine during protein synthesis. In mammals, arginine is classified as a semiessential or conditionally essential amino acid, depending on the developmental stage and health status of the individual.L-Arginine is associated with a decrease in cardiac index while stroke index is maintained in patients with severe sepsis. Resolution of shock at 72 hours is achieved by 40% and 24% of the patients in the L-Arginine and placebo cohorts, respectively. L-Arginine (450 mg/kg during a 15-minute period) amplifies and sustains the hyperemia (38%) and increases absolute brain blood flow after eNOS upregulation by chronic simvastatin treatment (2 mg/kg subcutaneously, daily for 14 days) in SV-129 mice.
Bromodomain IN-1 is a Bromodomain inhibitor extracted from patent WO2016069578A1, compound 4 [1].
Connexin mimetic peptide 40GAP27 is a biological active peptide. (This peptide corresponds to the GAP27 domain of the second extracellular loop of dominant vascular connexin (Cx40), designated as 40Gap 27. It was used to investigate mechanisms through which oxidant stress impairs communication via gap junctions. When administered, 40Gap27attenuates endothelium-dependent subintimal smooth muscle hyperpolarization.)