DC Chemicals Limited
China
Product Name: ST-271
Price: $500.0/100mg $800.0/250mg $1600.0/1g
Purity: 98.0%
Stocking Period: 3 Day
Contact: Tony Cao

Dayang Chem (Hangzhou) Co., Ltd.
China
Product Name: 2-Propenamide, 2-cyano-3-(4-hydroxy-3,5-bis(1-methylethyl)phenyl)-
Price: $Inquiry/100g $Inquiry/1kg $Inquiry/100kg $Inquiry/1000kg
Purity: 98.0%
Stocking Period: Inquiry
Contact: Ms Wang

106392-48-7

106392-48-7 structure

106392-48-7 structure

Name: ST-271
Chemical Name: (E)-2-cyano-3-[4-hydroxy-3,5-di(propan-2-yl)phenyl]prop-2-enamide
CAS Number: 106392-48-7
Molecular Formula: C₁₆H₂₀N₂O₂
Molecular Weight: 272.34200
Catalog: Research Areas Others
Create Date: 2016-08-17 06:20:02
Modify Date: 2024-01-03 10:26:43
ST271 is a potent inhibitor of protein tyrosine kinase (PTK).

Name	(E)-2-cyano-3-[4-hydroxy-3,5-di(propan-2-yl)phenyl]prop-2-enamide
Synonyms	st 271 ST-271 ST271

Description	ST271 is a potent inhibitor of protein tyrosine kinase (PTK).
Related Catalog	Signaling Pathways >> Others >> Others Research Areas >> Others
In Vitro	ST271 partially inhibits peptide phosphorylation in the membrane preparation and in permeabilized platelets[1]. ST271 (100 μM) causes complete inhibition of formation of inositol phosphates induced by FcγRII cross-linking, but also induces a small (< 30%) but significant inhibition of the response to thrombin and U46619[2].
References	[1]. Martinson EA, et al. Inhibition of phospholipase D of human platelets by protein tyrosine kinase inhibitors. Cell Mol Biol (Noisy-le-grand). 1994 Jul;40(5):627-34. [2]. Blake RA, et al. Fc gamma receptor II stimulated formation of inositol phosphates in human platelets is blocked by tyrosine kinase inhibitors and associated with tyrosine phosphorylation of the receptor.

Density	1.137g/cm3
Boiling Point	468.4ºC at 760mmHg
Molecular Formula	C₁₆H₂₀N₂O₂
Molecular Weight	272.34200
Flash Point	237.1ºC
Exact Mass	272.15200
PSA	88.10000
LogP	4.18098
Appearance	light yellow solid
Vapour Pressure	2.14E-09mmHg at 25°C
Index of Refraction	1.585
Storage condition	-20℃

HS Code	2926909090

HS Code	2926909090
Summary	HS:2926909090 other nitrile-function compounds VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:30.0%