35013-72-0

35013-72-0 structure

Name: Biotin NHS
Chemical Name: (2,5-dioxopyrrolidin-1-yl) 5-[(3aS,4S,6aR)-2-oxo-1,3,3a,4,6,6a-hexahydrothieno[3,4-d]imidazol-4-yl]pentanoate
CAS Number: 35013-72-0
Molecular Formula: C₁₄H₁₉N₃O₅S
Molecular Weight: 341.383
Catalog: Dye Reagents
Create Date: 2018-12-27 18:42:50
Modify Date: 2025-08-20 20:34:46
Biotin NHS is an amino reactive biotin reagent used in the preparation of biotinylated surfaces or polypeptides.

Name	(2,5-dioxopyrrolidin-1-yl) 5-[(3aS,4S,6aR)-2-oxo-1,3,3a,4,6,6a-hexahydrothieno[3,4-d]imidazol-4-yl]pentanoate
Synonyms	D-biotin N-hydroxysuccinimide ester biotin-N-hydroxysuccinimide ester (+)-Biotin N-hydroxysuccinimide ester 2,5-Pyrrolidinedione, 1-[[5-[(3aS,4S,6aR)-hexahydro-2-oxo-1H-thieno[3,4-d]imidazol-4-yl]-1-oxopentyl]oxy]- N-hydroxysuccinimide-biotin BNHS 1-({5-[(3aS,4S,6aR)-2-Oxohexahydro-1H-thieno[3,4-d]imidazol-4-yl]pentanoyl}oxy)-2,5-pyrrolidinedione Biotinyl-N-hydroxy-succinimide (+)-Biotin N-succinimidyl ester,d-Biotin NHS ester,BNHS NHS-Biotin N-(D-Biotinyloxy)succinimide (+)-Biotin N-succinimidyl ester N-Succinimidyl D-Biotinate Biotin-OSu N-Hydroxysuccinimidobiotin D-Biotin-Osu 2,5-Dioxopyrrolidin-1-yl 5-((3aS,4S,6aR)-2-oxohexahydro-1H-thieno[3,4-d]imidazol-4-yl)pentanoate MFCD00078531 d-Biotin NHS ester 1-({5-[(3aS,4S,6aR)-2-Oxohexahydro-1H-thieno[3,4-d]imidazol-4-yl]pentanoyl}oxy)pyrrolidine-2,5-dione Biotin NHS

Description	Biotin NHS is an amino reactive biotin reagent used in the preparation of biotinylated surfaces or polypeptides.
Related Catalog	Signaling Pathways >> Others >> Others Dye Reagents Research Areas >> Others
References	[1]. Wojchowski DM et al. Hybridoma production by simplified avidin-mediated electrofusion. J Immunol Methods. 1986 Jun 24;90(2):173-7. [2]. Ngo TT et al. Biotinyl-glucose-6-phosphate dehydrogenase preparation, kinetics, and modulation by avidin. Appl Biochem Biotechnol. 1982 Nov;7(6):443-54.

Density	1.5±0.1 g/cm3
Melting Point	212-214 °C
Molecular Formula	C₁₄H₁₉N₃O₅S
Molecular Weight	341.383
Exact Mass	341.104553
PSA	130.11000
LogP	-1.41
Index of Refraction	1.616
Storage condition	−20°C
Stability	Stable. Incompatible with strong oxidizing agents.
Water Solubility	DMF: ≤50 mg/mL Stable for at least one month in dry DMF

Personal Protective Equipment	Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter
Hazard Codes	Xn
Safety Phrases	S22-S24/25
RIDADR	NONH for all modes of transport
WGK Germany	3

6066-82-6

58-85-5

~99%

35013-72-0

Literature: Journal of the American Chemical Society, , vol. 129, # 45 p. 13987 - 13996

58-85-5

35013-72-0

Literature: WO2007/131286 A1, ; Page/Page column 70 ;

6066-82-6

101187-31-9

~88%

35013-72-0

Literature: Journal of Medicinal Chemistry, , vol. 27, # 11 p. 1406 - 1410

74124-79-1

58-85-5

35013-72-0

Literature: Tetrahedron, , vol. 57, # 49 p. 9859 - 9866