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101187-40-0

101187-40-0 structure
101187-40-0 structure
  • Name: PROTAC Linker 15
  • Chemical Name: tert-butyl N-[2-[2-[2-(2-aminoethoxy)ethoxy]ethoxy]ethyl]carbamate
  • CAS Number: 101187-40-0
  • Molecular Formula: C13H28N2O5
  • Molecular Weight: 292.37200
  • Catalog: Signaling Pathways PROTAC PROTAC Linker
  • Create Date: 2018-12-25 17:57:45
  • Modify Date: 2024-01-02 18:46:00
  • PROTAC Linker 15 is a PROTAC linker, which refers to the alkyl/ether composition. PROTAC Linker 15 can be used in the synthesis of a series of PROTACs. PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].

Name tert-butyl N-[2-[2-[2-(2-aminoethoxy)ethoxy]ethoxy]ethyl]carbamate
Synonyms t-Boc-N-Amido-PEG3-Amine
13-AMINO-5,8,11-TRIOXA-2-AZATRIDECANOIC ACID 1,1-DIMETHYLETHYL ESTER
1-Boc-amine-11-amino-3,6,9-trioxaundecane
Description PROTAC Linker 15 is a PROTAC linker, which refers to the alkyl/ether composition. PROTAC Linker 15 can be used in the synthesis of a series of PROTACs. PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
Related Catalog
Target

Alkyl/ether

References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562.

Density 1.05
Molecular Formula C13H28N2O5
Molecular Weight 292.37200
Exact Mass 292.20000
PSA 92.04000
LogP 1.61080
Hazard Codes Xi
HS Code 2924199090
HS Code 2924199090
Summary 2924199090. other acyclic amides (including acyclic carbamates) and their derivatives; salts thereof. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%