Name | 3,6,9-Trioxaundecane-1,11-Diamine |
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Synonyms |
EINECS 213-206-2
2,2'-[oxybis(ethane-2,1-diyloxy)]diethanamine Ethanamine, 2,2'-[oxybis(2,1-ethanediyloxy)]bis- 2,2'-[Oxybis(ethylenoxy)]diethylamine 2,2'-[Oxybis(2,1-ethanediyloxy)]diethanamine MFCD00628164 3,6,9-trioxaundecamethylenediamine |
Description | Amino-PEG3-C2-Amine is a PEG-based (3 units) PROTAC linker can be used in the synthesis of PROTACs. |
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Related Catalog | |
In Vitro | PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins. |
References |
Density | 1.0±0.1 g/cm3 |
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Boiling Point | 291.1±25.0 °C at 760 mmHg |
Molecular Formula | C8H20N2O3 |
Molecular Weight | 192.256 |
Flash Point | 131.8±16.8 °C |
Exact Mass | 192.147400 |
PSA | 79.73000 |
LogP | -1.94 |
Vapour Pressure | 0.0±0.6 mmHg at 25°C |
Index of Refraction | 1.462 |
Symbol |
GHS05, GHS07 |
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Signal Word | Danger |
Hazard Statements | H315-H318-H335 |
Precautionary Statements | P261-P280-P305 + P351 + P338 |
Personal Protective Equipment | Eyeshields;full-face respirator (US);Gloves;multi-purpose combination respirator cartridge (US);type ABEK (EN14387) respirator filter |
Hazard Codes | Xi: Irritant; |
Risk Phrases | R37/38;R41 |
Safety Phrases | S26-S39 |
RIDADR | NONH for all modes of transport |
HS Code | 2922199090 |
~97% 929-75-9 |
Literature: EVONIK DEGUSSA GmbH; Klasovsky, Florian; Tacke, Thomas; Pfeffer, Jan Christoph; Haas, Thomas; Beller, Matthias; Martin, Andreas; Deutsch, Jens; Koeckritz, Angela; Imm, Sebastian; Haberland, Juergen Patent: US2013/331580 A1, 2013 ; Location in patent: Paragraph 0063 ; |
~93% 929-75-9 |
Literature: Gunzenhauser; Biala; Strazewski Nucleosides and Nucleotides, 1999 , vol. 18, # 6-7 p. 1223 - 1224 |
~77% 929-75-9 |
Literature: Lill, Andreas; Scholich, Klaus; Stark, Holger Tetrahedron Letters, 2013 , vol. 54, # 49 p. 6682 - 6686 |
~% 929-75-9 |
Literature: US4705886 A1, ; |
~% 929-75-9 |
Literature: Journal of Organic Chemistry USSR (English Translation), , vol. 16, p. 1124 - 1129 Zhurnal Organicheskoi Khimii, , vol. 16, # 6 p. 1301 - 1307 |
~% 929-75-9 |
Literature: US2709178 , ; |
~% 929-75-9 |
Literature: Synthetic Communications, , vol. 21, # 1 p. 79 - 84 |
~% 929-75-9 |
Literature: Journal of Organic Chemistry, , vol. 63, # 5 p. 1727 - 1729 |
Precursor 8 | |
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DownStream 10 | |
HS Code | 2922199090 |
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Summary | 2922199090. other amino-alcohols, other than those containing more than one kind of oxygen function, their ethers and esters; salts thereof. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0% |