- Shanghai Jizhi Biochemical Technology Co., Ltd
- China
- Product Name: PROTAC Linker 16
- Price: ￥76.0/1g ￥296.0/10g ￥686.0/25g ￥186.0/5g
- Purity: 97.0%
- Stocking Period: 1 Day
- Contact: Liu jia
- Dayang Chem (Hangzhou) Co., Ltd.
- China
- Product Name: ((OXYBIS(ETHANE-2,1-DIYL))BIS(OXY))BIS(ETHANE-2,1-DIYL) BIS(4-METHYLBENZENESULFONATE)
- Price: $Inquiry/100g $Inquiry/1kg $Inquiry/100kg $Inquiry/1000kg
- Purity: 98.0%
- Stocking Period: Inquiry
- Contact: Ms Wang
37860-51-8
37860-51-8 structure
- Name: PROTAC Linker 16
- Chemical Name: Tetraethylene Glycol DI-P-Tosylate
- CAS Number: 37860-51-8
- Molecular Formula: C22H30O9S2
- Molecular Weight: 502.59800
- Catalog: Chemical reagent Organic reagent Tosylate
- Create Date: 2018-03-13 08:00:00
- Modify Date: 2024-01-01 23:46:36
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PROTAC Linker 16 is a polyethylene glycol (PEG)-based PROTAC linker. PROTAC Linker 16 can be used in the synthesis of a series of PROTACs. PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
| Name | Tetraethylene Glycol DI-P-Tosylate |
|---|---|
| Synonyms |
TETRAETHYLENE GLYCOL DI-P-TOSYLATE
Tetraethylene Glycol Bis(p-toluenesulfonate) Bis[2-[2-(p-toluenesulfonyloxy)ethoxy]ethyl] Ether ((Oxybis(ethane-2,1-diyl))bis(oxy))bis(ethane-2,1-diyl) bis(4-methylbenzenesulfonate) Bis[2-(2-tosyloxyethoxy)ethyl] Ether MFCD00075239 |
| Description | PROTAC Linker 16 is a polyethylene glycol (PEG)-based PROTAC linker. PROTAC Linker 16 can be used in the synthesis of a series of PROTACs. PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1]. |
|---|---|
| Related Catalog | |
| Target |
PEGs |
| References |
| Density | 1.242 g/mL at 25ºC(lit.) |
|---|---|
| Boiling Point | 635ºC at 760 mmHg |
| Molecular Formula | C22H30O9S2 |
| Molecular Weight | 502.59800 |
| Flash Point | >230 °F |
| Exact Mass | 502.13300 |
| PSA | 131.19000 |
| LogP | 4.62560 |
| Index of Refraction | n20/D 1.53(lit.) |
| Symbol |
GHS07 |
|---|---|
| Signal Word | Warning |
| Hazard Statements | H315-H319-H335 |
| Precautionary Statements | P261-P305 + P351 + P338 |
| Personal Protective Equipment | Eyeshields;full-face respirator (US);Gloves;multi-purpose combination respirator cartridge (US);type ABEK (EN14387) respirator filter |
| Hazard Codes | Xi |
| Risk Phrases | R36/37/38 |
| Safety Phrases | S26 |
| RIDADR | NONH for all modes of transport |
| WGK Germany | 3 |
| HS Code | 2909309090 |
| HS Code | 2909309090 |
|---|---|
| Summary | 2909309090 other aromatic ethers and their halogenated, sulphonated, nitrated or nitrosated derivatives VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:5.5% General tariff:30.0% |