PROTAC Linker 15

Modify Date: 2025-08-23 11:35:20

PROTAC Linker 15 Structure
PROTAC Linker 15 structure
Common Name PROTAC Linker 15
CAS Number 101187-40-0 Molecular Weight 292.37200
Density 1.05 Boiling Point N/A
Molecular Formula C13H28N2O5 Melting Point N/A
MSDS Chinese Flash Point N/A

 Use of PROTAC Linker 15


PROTAC Linker 15 is a PROTAC linker, which refers to the alkyl/ether composition. PROTAC Linker 15 can be used in the synthesis of a series of PROTACs. PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].

 Names

Name tert-butyl N-[2-[2-[2-(2-aminoethoxy)ethoxy]ethoxy]ethyl]carbamate
Synonym More Synonyms

 PROTAC Linker 15 Biological Activity

Description PROTAC Linker 15 is a PROTAC linker, which refers to the alkyl/ether composition. PROTAC Linker 15 can be used in the synthesis of a series of PROTACs. PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
Related Catalog
Target

Alkyl/ether

References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562.

 Chemical & Physical Properties

Density 1.05
Molecular Formula C13H28N2O5
Molecular Weight 292.37200
Exact Mass 292.20000
PSA 92.04000
LogP 1.61080
InChIKey CUPBLDPRUBNAIE-UHFFFAOYSA-N
SMILES CC(C)(C)OC(=O)NCCOCCOCCOCCN

 Safety Information

Hazard Codes Xi
HS Code 2924199090

 Customs

HS Code 2924199090
Summary 2924199090. other acyclic amides (including acyclic carbamates) and their derivatives; salts thereof. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%

 Synonyms

t-Boc-N-Amido-PEG3-Amine
13-AMINO-5,8,11-TRIOXA-2-AZATRIDECANOIC ACID 1,1-DIMETHYLETHYL ESTER
1-Boc-amine-11-amino-3,6,9-trioxaundecane
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