PROTAC Linker 15 structure
|
Common Name | PROTAC Linker 15 | ||
|---|---|---|---|---|
| CAS Number | 101187-40-0 | Molecular Weight | 292.37200 | |
| Density | 1.05 | Boiling Point | N/A | |
| Molecular Formula | C13H28N2O5 | Melting Point | N/A | |
| MSDS | Chinese | Flash Point | N/A | |
Use of PROTAC Linker 15PROTAC Linker 15 is a PROTAC linker, which refers to the alkyl/ether composition. PROTAC Linker 15 can be used in the synthesis of a series of PROTACs. PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1]. |
| Name | tert-butyl N-[2-[2-[2-(2-aminoethoxy)ethoxy]ethoxy]ethyl]carbamate |
|---|---|
| Synonym | More Synonyms |
| Description | PROTAC Linker 15 is a PROTAC linker, which refers to the alkyl/ether composition. PROTAC Linker 15 can be used in the synthesis of a series of PROTACs. PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1]. |
|---|---|
| Related Catalog | |
| Target |
Alkyl/ether |
| References |
| Density | 1.05 |
|---|---|
| Molecular Formula | C13H28N2O5 |
| Molecular Weight | 292.37200 |
| Exact Mass | 292.20000 |
| PSA | 92.04000 |
| LogP | 1.61080 |
| InChIKey | CUPBLDPRUBNAIE-UHFFFAOYSA-N |
| SMILES | CC(C)(C)OC(=O)NCCOCCOCCOCCN |
| Hazard Codes | Xi |
|---|---|
| HS Code | 2924199090 |
|
~97%
PROTAC Linker 15 CAS#:101187-40-0 |
| Literature: Tetrahedron, , vol. 68, # 52 p. 10818 - 10826 |
|
~32%
PROTAC Linker 15 CAS#:101187-40-0 |
| Literature: WO2005/30258 A2, ; Page/Page column 115 ; WO 2005/030258 A2 |
|
~78%
PROTAC Linker 15 CAS#:101187-40-0 |
| Literature: Journal of the American Chemical Society, , vol. 134, # 1 p. 83 - 86 |
|
~26%
PROTAC Linker 15 CAS#:101187-40-0 |
| Literature: Journal of Organic Chemistry, , vol. 66, # 11 p. 3709 - 3716 |
|
~98%
PROTAC Linker 15 CAS#:101187-40-0 |
| Literature: Tetrahedron Letters, , vol. 39, # 48 p. 8799 - 8802 |
|
~%
PROTAC Linker 15 CAS#:101187-40-0 |
| Literature: Journal of the American Chemical Society, , vol. 134, # 1 p. 83 - 86 |
|
~%
PROTAC Linker 15 CAS#:101187-40-0 |
| Literature: Journal of the American Chemical Society, , vol. 134, # 1 p. 83 - 86 |
|
~%
PROTAC Linker 15 CAS#:101187-40-0 |
| Literature: Journal of the American Chemical Society, , vol. 134, # 1 p. 83 - 86 |
| Precursor 9 | |
|---|---|
| DownStream 1 | |
| HS Code | 2924199090 |
|---|---|
| Summary | 2924199090. other acyclic amides (including acyclic carbamates) and their derivatives; salts thereof. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0% |
| t-Boc-N-Amido-PEG3-Amine |
| 13-AMINO-5,8,11-TRIOXA-2-AZATRIDECANOIC ACID 1,1-DIMETHYLETHYL ESTER |
| 1-Boc-amine-11-amino-3,6,9-trioxaundecane |