Boc-N-Amido-PEG3-azide

Modify Date: 2024-01-14 11:17:56

Boc-N-Amido-PEG3-azide Structure
Boc-N-Amido-PEG3-azide structure
Common Name Boc-N-Amido-PEG3-azide
CAS Number 642091-68-7 Molecular Weight 318.36900
Density N/A Boiling Point N/A
Molecular Formula C13H26N4O5 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Boc-N-Amido-PEG3-azide


Boc-N-Amido-PEG3-azide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

 Names

Name tert-butyl N-[2-[2-[2-(2-azidoethoxy)ethoxy]ethoxy]ethyl]carbamate
Synonym More Synonyms

 Boc-N-Amido-PEG3-azide Biological Activity

Description Boc-N-Amido-PEG3-azide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

 Chemical & Physical Properties

Molecular Formula C13H26N4O5
Molecular Weight 318.36900
Exact Mass 318.19000
PSA 119.26000
LogP 1.52836

 Synonyms

5,8,11-Trioxa-2-azatridecanoic acid,13-azido-,1,1-dimethylethyl ester
t-Boc-N-Amido-PEG3-Azide
1-Boc-amine-11-azido-3,6,9-trioxaundecane
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