2128735-28-2

2128735-28-2 structure

2128735-28-2 structure

Name: T-Boc-n-amido-peg5-ms
Chemical Name: Boc-N-Amido-PEG5-Ms
CAS Number: 2128735-28-2
Molecular Formula: C₁₆H₃₃NO₉S
Molecular Weight: 415.50
Catalog: Signaling Pathways PROTAC PROTAC Linker
Create Date: 2020-06-01 11:48:46
Modify Date: 2024-01-30 12:31:52
Boc-N-Amido-PEG5-Ms is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

Name	Boc-N-Amido-PEG5-Ms
Synonyms	MFCD31536757

Description	Boc-N-Amido-PEG5-Ms is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> PROTAC >> PROTAC Linker
Target	PEGs Alkyl/ether
In Vitro	PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References	[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

Molecular Formula	C₁₆H₃₃NO₉S
Molecular Weight	415.50