t-boc-N-amido-PEG7-azide

Modify Date: 2024-01-09 19:08:46

t-boc-N-amido-PEG7-azide Structure
t-boc-N-amido-PEG7-azide structure
Common Name t-boc-N-amido-PEG7-azide
CAS Number 206265-96-5 Molecular Weight 494.58
Density N/A Boiling Point N/A
Molecular Formula C21H42N4O9 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of t-boc-N-amido-PEG7-azide


Boc-NH-PEG7-azide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

 Names

Name Boc-NH-PEG7-azide

 t-boc-N-amido-PEG7-azide Biological Activity

Description Boc-NH-PEG7-azide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

 Chemical & Physical Properties

Molecular Formula C21H42N4O9
Molecular Weight 494.58