t-Boc-N-Amido-PEG4-propargyl

Modify Date: 2024-01-31 11:02:25

t-Boc-N-Amido-PEG4-propargyl Structure
t-Boc-N-Amido-PEG4-propargyl structure
Common Name t-Boc-N-Amido-PEG4-propargyl
CAS Number 1219810-90-8 Molecular Weight 331.40
Density N/A Boiling Point N/A
Molecular Formula C16H29NO6 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of t-Boc-N-Amido-PEG4-propargyl


Boc-N-Amido-PEG4-propargyl is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

 Names

Name Boc-N-Amido-PEG4-propargyl

 t-Boc-N-Amido-PEG4-propargyl Biological Activity

Description Boc-N-Amido-PEG4-propargyl is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

Alkyl/ether

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

 Chemical & Physical Properties

Molecular Formula C16H29NO6
Molecular Weight 331.40
Storage condition 2-8℃