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2062663-67-4

2062663-67-4 structure
2062663-67-4 structure
  • Name: t-Boc-N-Amido-PEG5-propargyl
  • Chemical Name: Boc-NH-PEG5-propargyl
  • CAS Number: 2062663-67-4
  • Molecular Formula: C18H33NO7
  • Molecular Weight: 375.46
  • Catalog: Signaling Pathways PROTAC PROTAC Linker
  • Create Date: 2020-06-01 20:33:30
  • Modify Date: 2024-01-05 16:43:57
  • Boc-NH-PEG5-propargyl is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

Name Boc-NH-PEG5-propargyl
Synonyms MFCD30534431
Description Boc-NH-PEG5-propargyl is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

Molecular Formula C18H33NO7
Molecular Weight 375.46