t-boc-N-amido-PEG9-azide

Modify Date: 2024-01-09 21:44:33

t-boc-N-amido-PEG9-azide Structure
t-boc-N-amido-PEG9-azide structure
Common Name t-boc-N-amido-PEG9-azide
CAS Number 2112731-50-5 Molecular Weight 582.68
Density N/A Boiling Point N/A
Molecular Formula C25H50N4O11 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of t-boc-N-amido-PEG9-azide


Boc-NH-PEG9-azide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

 Names

Name Boc-NH-PEG9-azide

 t-boc-N-amido-PEG9-azide Biological Activity

Description Boc-NH-PEG9-azide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

Alkyl/ether

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

 Chemical & Physical Properties

Molecular Formula C25H50N4O11
Molecular Weight 582.68