Top Suppliers:I want be here


1347750-75-7

1347750-75-7 structure
1347750-75-7 structure
  • Name: Boc-N-amido-PEG3-acid
  • Chemical Name: 2,2-Dimethyl-4-oxo-3,8,11,14-tetraoxa-5-azaheptadecan-17-oic acid
  • CAS Number: 1347750-75-7
  • Molecular Formula: C14H27NO7
  • Molecular Weight: 321.367
  • Catalog: Signaling Pathways PROTAC PROTAC Linker
  • Create Date: 2018-06-07 08:28:10
  • Modify Date: 2024-01-08 05:10:13
  • Boc-N-amido-PEG3-acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

Name 2,2-Dimethyl-4-oxo-3,8,11,14-tetraoxa-5-azaheptadecan-17-oic acid
Synonyms 2,2-Dimethyl-4-oxo-3,8,11,14-tetraoxa-5-azaheptadecan-17-oic acid
3,8,11,14-Tetraoxa-5-azaheptadecan-17-oic acid, 2,2-dimethyl-4-oxo-
Boc-9-AMino-4,7-Dioxanonanoic acid
t-Boc-N-amido-PEG3-acid
Description Boc-N-amido-PEG3-acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

Alkyl/ether

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

Density 1.1±0.1 g/cm3
Boiling Point 471.1±40.0 °C at 760 mmHg
Molecular Formula C14H27NO7
Molecular Weight 321.367
Flash Point 238.7±27.3 °C
Exact Mass 321.178741
LogP 0.22
Vapour Pressure 0.0±2.5 mmHg at 25°C
Index of Refraction 1.465
Hazard Codes Xn