Boc-N-amido-PEG3-acid

Modify Date: 2024-01-08 05:10:13

Boc-N-amido-PEG3-acid Structure
Boc-N-amido-PEG3-acid structure
Common Name Boc-N-amido-PEG3-acid
CAS Number 1347750-75-7 Molecular Weight 321.367
Density 1.1±0.1 g/cm3 Boiling Point 471.1±40.0 °C at 760 mmHg
Molecular Formula C14H27NO7 Melting Point N/A
MSDS N/A Flash Point 238.7±27.3 °C

 Use of Boc-N-amido-PEG3-acid


Boc-N-amido-PEG3-acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

 Names

Name 2,2-Dimethyl-4-oxo-3,8,11,14-tetraoxa-5-azaheptadecan-17-oic acid
Synonym More Synonyms

 Boc-N-amido-PEG3-acid Biological Activity

Description Boc-N-amido-PEG3-acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

Alkyl/ether

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

 Chemical & Physical Properties

Density 1.1±0.1 g/cm3
Boiling Point 471.1±40.0 °C at 760 mmHg
Molecular Formula C14H27NO7
Molecular Weight 321.367
Flash Point 238.7±27.3 °C
Exact Mass 321.178741
LogP 0.22
Vapour Pressure 0.0±2.5 mmHg at 25°C
Index of Refraction 1.465

 Safety Information

Hazard Codes Xn

 Synonyms

2,2-Dimethyl-4-oxo-3,8,11,14-tetraoxa-5-azaheptadecan-17-oic acid
3,8,11,14-Tetraoxa-5-azaheptadecan-17-oic acid, 2,2-dimethyl-4-oxo-
Boc-9-AMino-4,7-Dioxanonanoic acid
t-Boc-N-amido-PEG3-acid
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