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1807534-77-5

1807534-77-5 structure
1807534-77-5 structure
  • Name: Fluorescein-PEG3-NH-Boc
  • Chemical Name: Fluorescein-PEG3-(N-Boc)-Amine
  • CAS Number: 1807534-77-5
  • Molecular Formula: C34H39N3O10S
  • Molecular Weight: 681.753
  • Catalog: Signaling Pathways PROTAC PROTAC Linker
  • Create Date: 2018-07-16 15:08:00
  • Modify Date: 2024-01-08 08:52:05
  • Fluorescein-PEG3-NH-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

Name Fluorescein-PEG3-(N-Boc)-Amine
Synonyms 5-{[(2,2-Dimethyl-4-oxo-3,8,11,14-tetraoxa-5-azahexadecan-16-yl)carbamothioyl]amino}-2-(6-hydroxy-3-oxo-3H-xanthen-9-yl)benzoic acid
MFCD23726634
Benzoic acid, 5-[(17,17-dimethyl-15-oxo-1-thioxo-5,8,11,16-tetraoxa-2,14-diazaoctadec-1-yl)amino]-2-(6-hydroxy-3-oxo-3H-xanthen-9-yl)-
Description Fluorescein-PEG3-NH-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

Density 1.4±0.1 g/cm3
Molecular Formula C34H39N3O10S
Molecular Weight 681.753
Exact Mass 681.235596
LogP 2.92
Index of Refraction 1.650