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90736-68-8

90736-68-8 structure
90736-68-8 structure
  • Name: Propenyl-PEG3-Propenyl
  • Chemical Name: 3-[2-[2-(2-prop-2-enoxyethoxy)ethoxy]ethoxy]prop-1-ene
  • CAS Number: 90736-68-8
  • Molecular Formula: C12H22O4
  • Molecular Weight: 230.30100
  • Catalog: Signaling Pathways PROTAC PROTAC Linker
  • Create Date: 2017-09-22 16:50:14
  • Modify Date: 2024-01-09 11:19:22
  • Propenyl-PEG3-Propenyl is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

Name 3-[2-[2-(2-prop-2-enoxyethoxy)ethoxy]ethoxy]prop-1-ene
Synonyms 4,7,10,13-Tetraoxahexadeca-1,15-diene
triethylene glycol diallyl ether
Propenyl-PEG3-Propenyl
Description Propenyl-PEG3-Propenyl is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

Molecular Formula C12H22O4
Molecular Weight 230.30100
Exact Mass 230.15200
PSA 36.92000
LogP 1.42480