Propenyl-PEG3-Propenyl

Modify Date: 2024-01-09 11:19:22

Propenyl-PEG3-Propenyl Structure
Propenyl-PEG3-Propenyl structure
Common Name Propenyl-PEG3-Propenyl
CAS Number 90736-68-8 Molecular Weight 230.30100
Density N/A Boiling Point N/A
Molecular Formula C12H22O4 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Propenyl-PEG3-Propenyl


Propenyl-PEG3-Propenyl is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

 Names

Name 3-[2-[2-(2-prop-2-enoxyethoxy)ethoxy]ethoxy]prop-1-ene
Synonym More Synonyms

 Propenyl-PEG3-Propenyl Biological Activity

Description Propenyl-PEG3-Propenyl is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

 Chemical & Physical Properties

Molecular Formula C12H22O4
Molecular Weight 230.30100
Exact Mass 230.15200
PSA 36.92000
LogP 1.42480

 Synonyms

4,7,10,13-Tetraoxahexadeca-1,15-diene
triethylene glycol diallyl ether
Propenyl-PEG3-Propenyl