Propynyl-PEG1-Ac

Modify Date: 2025-10-15 19:17:59

Propynyl-PEG1-Ac Structure
Propynyl-PEG1-Ac structure
Common Name Propynyl-PEG1-Ac
CAS Number 944561-45-9 Molecular Weight 158.15
Density N/A Boiling Point N/A
Molecular Formula C7H10O4 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Propynyl-PEG1-Ac


Propynyl-PEG1-Ac is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

 Names

Name Propynyl-PEG1-Ac
Synonym More Synonyms

 Propynyl-PEG1-Ac Biological Activity

Description Propynyl-PEG1-Ac is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

 Chemical & Physical Properties

Molecular Formula C7H10O4
Molecular Weight 158.15
InChIKey OFHMCWOCIIQXLU-UHFFFAOYSA-N
SMILES C#CCOCCOCC(=O)O

 Synonyms

MFCD30469070
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