Lenalidomide-PEG1-azide

Modify Date: 2025-08-27 14:49:20

Lenalidomide-PEG1-azide Structure
Lenalidomide-PEG1-azide structure
Common Name Lenalidomide-PEG1-azide
CAS Number 2185795-67-7 Molecular Weight 386.36
Density N/A Boiling Point N/A
Molecular Formula C17H18N6O5 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Lenalidomide-PEG1-azide


Lenalidomide-PEG1-azide is a E3 ligase lgand-linker conjugate. Lenalidomide-PEG1-azide incorporates the Lenalidomide based cereblon ligand and a linker. Lenalidomide-PEG1-azide can be used to design a PROTAC BRD4 Degrader-2 (HY-133136)[1].

 Names

Name Lenalidomide-PEG1-azide

 Lenalidomide-PEG1-azide Biological Activity

Description Lenalidomide-PEG1-azide is a E3 ligase lgand-linker conjugate. Lenalidomide-PEG1-azide incorporates the Lenalidomide based cereblon ligand and a linker. Lenalidomide-PEG1-azide can be used to design a PROTAC BRD4 Degrader-2 (HY-133136)[1].
Related Catalog
References

[1]. Zhang F, et al. Discovery of a new class of PROTAC BRD4 degraders based on a dihydroquinazolinone derivative and lenalidomide/pomalidomide. Bioorg Med Chem. 2020 Jan 1;28(1):115228.

 Chemical & Physical Properties

Molecular Formula C17H18N6O5
Molecular Weight 386.36
InChIKey GGIQROQPJRHRQW-UHFFFAOYSA-N
SMILES [N-]=[N+]=NCCOCC(=O)Nc1cccc2c1CN(C1CCC(=O)NC1=O)C2=O

 Safety Information

Hazard Codes Xi
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