N-Boc-N-bis(PEG1-azide)

Modify Date: 2024-01-03 17:59:27

N-Boc-N-bis(PEG1-azide) Structure
N-Boc-N-bis(PEG1-azide) structure
Common Name N-Boc-N-bis(PEG1-azide)
CAS Number 2100306-79-2 Molecular Weight 343.38
Density N/A Boiling Point N/A
Molecular Formula C13H25N7O4 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of N-Boc-N-bis(PEG1-azide)


N-Boc-N-bis(C2-PEG1-azide) is an alkyl/ether-based PROTAC linker that can be used in the synthesis of PROTACs[1].

 Names

Name N-Boc-N-bis(C2-PEG1-azide)

 N-Boc-N-bis(PEG1-azide) Biological Activity

Description N-Boc-N-bis(C2-PEG1-azide) is an alkyl/ether-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

Alkyl/ether

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

 Chemical & Physical Properties

Molecular Formula C13H25N7O4
Molecular Weight 343.38

 Safety Information

Hazard Codes Xi