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2100306-86-1

2100306-86-1 structure
2100306-86-1 structure
  • Name: N-Boc-N-bis(PEG2-propargyl)
  • Chemical Name: N-Boc-N-bis(PEG2-propargyl)
  • CAS Number: 2100306-86-1
  • Molecular Formula: C19H31NO6
  • Molecular Weight: 369.45
  • Catalog: Signaling Pathways PROTAC PROTAC Linker
  • Create Date: 2020-06-01 17:57:18
  • Modify Date: 2023-01-06 16:49:14
  • N-Boc-N-bis(PEG2-propargyl) is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

Name N-Boc-N-bis(PEG2-propargyl)
Synonyms MFCD30730382
Description N-Boc-N-bis(PEG2-propargyl) is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

Molecular Formula C19H31NO6
Molecular Weight 369.45