2093153-08-1

2093153-08-1 structure

2093153-08-1 structure

Name: N-Boc-N-bis(PEG4-NHS ester)
Chemical Name: N-Boc-N-bis(PEG4-NHS ester)
CAS Number: 2093153-08-1
Molecular Formula: C₃₅H₅₇N₃O₁₈
Molecular Weight: 807.84
Catalog: Signaling Pathways PROTAC PROTAC Linker
Create Date: 2020-06-01 18:37:06
Modify Date: 2024-01-15 11:32:29
N-Boc-N-bis(PEG4-NHS ester) is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

Name	N-Boc-N-bis(PEG4-NHS ester)
Synonyms	MFCD29912670

Description	N-Boc-N-bis(PEG4-NHS ester) is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> PROTAC >> PROTAC Linker
Target	PEGs Alkyl/ether
In Vitro	PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References	[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

Molecular Formula	C₃₅H₅₇N₃O₁₈
Molecular Weight	807.84