2185795-67-7

2185795-67-7 structure

Name: Lenalidomide-PEG1-azide
Chemical Name: Lenalidomide-PEG1-azide
CAS Number: 2185795-67-7
Molecular Formula: C₁₇H₁₈N₆O₅
Molecular Weight: 386.36
Catalog: Signaling Pathways PROTAC E3 Ligase Ligand-Linker Conjugate
Create Date: 2020-04-11 15:52:24
Modify Date: 2025-08-27 14:49:20
Lenalidomide-PEG1-azide is a E3 ligase lgand-linker conjugate. Lenalidomide-PEG1-azide incorporates the Lenalidomide based cereblon ligand and a linker. Lenalidomide-PEG1-azide can be used to design a PROTAC BRD4 Degrader-2 (HY-133136)[1].

Name	Lenalidomide-PEG1-azide

Description	Lenalidomide-PEG1-azide is a E3 ligase lgand-linker conjugate. Lenalidomide-PEG1-azide incorporates the Lenalidomide based cereblon ligand and a linker. Lenalidomide-PEG1-azide can be used to design a PROTAC BRD4 Degrader-2 (HY-133136)[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> PROTAC >> E3 Ligase Ligand-Linker Conjugate
References	[1]. Zhang F, et al. Discovery of a new class of PROTAC BRD4 degraders based on a dihydroquinazolinone derivative and lenalidomide/pomalidomide. Bioorg Med Chem. 2020 Jan 1;28(1):115228.

Molecular Formula	C₁₇H₁₈N₆O₅
Molecular Weight	386.36

Hazard Codes	Xi