Fmoc-PEG1-NHS ester

Modify Date: 2024-01-10 09:55:55

Fmoc-PEG1-NHS ester Structure
Fmoc-PEG1-NHS ester structure
Common Name Fmoc-PEG1-NHS ester
CAS Number 1807521-05-6 Molecular Weight 452.46
Density N/A Boiling Point N/A
Molecular Formula C24H24N2O7 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Fmoc-PEG1-NHS ester


Fmoc-PEG1-CH2CH2-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

 Names

Name Fmoc-PEG1-CH2CH2-NHS ester

 Fmoc-PEG1-NHS ester Biological Activity

Description Fmoc-PEG1-CH2CH2-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

Alkyl/ether

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

 Chemical & Physical Properties

Molecular Formula C24H24N2O7
Molecular Weight 452.46
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