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1027371-75-0

1027371-75-0 structure
1027371-75-0 structure
  • Name: m-PEG1-NHS ester
  • Chemical Name: m-PEG1-NHS ester
  • CAS Number: 1027371-75-0
  • Molecular Formula: C8H11NO5
  • Molecular Weight: 201.18
  • Catalog: Signaling Pathways PROTAC PROTAC Linker
  • Create Date: 2020-04-10 12:13:23
  • Modify Date: 2024-01-11 16:05:29
  • m-PEG1-NHS ester is a PEG/Alkyl/ether-based PROTAC linker can be used in the synthesis of PROTACs.

Name m-PEG1-NHS ester
Synonyms MFCD20229579
Description m-PEG1-NHS ester is a PEG/Alkyl/ether-based PROTAC linker can be used in the synthesis of PROTACs.
Related Catalog
Target

PEGs

Alkyl/ether

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
References

[1]. Lepage ML, et al. Design, synthesis and photochemical properties of the first examples of iminosugar clustersbased on fluorescent cores. Beilstein J Org Chem. 2015 May 6;11:659-67.

Molecular Formula C8H11NO5
Molecular Weight 201.18
Hazard Codes Xi