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1807521-05-6

1807521-05-6 structure
1807521-05-6 structure
  • Name: Fmoc-PEG1-NHS ester
  • Chemical Name: Fmoc-PEG1-CH2CH2-NHS ester
  • CAS Number: 1807521-05-6
  • Molecular Formula: C24H24N2O7
  • Molecular Weight: 452.46
  • Catalog: Signaling Pathways PROTAC PROTAC Linker
  • Create Date: 2020-04-08 20:34:18
  • Modify Date: 2024-01-10 09:55:55
  • Fmoc-PEG1-CH2CH2-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

Name Fmoc-PEG1-CH2CH2-NHS ester
Description Fmoc-PEG1-CH2CH2-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

Alkyl/ether

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

Molecular Formula C24H24N2O7
Molecular Weight 452.46