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1314378-14-7

1314378-14-7 structure
1314378-14-7 structure
  • Name: Fmoc-PEG4-NHS ester
  • Chemical Name: 9H-Fluoren-9-ylmethyl {15-[(2,5-dioxo-1-pyrrolidinyl)oxy]-15-oxo-3,6,9,12-tetraoxapentadec-1-yl}carbamate
  • CAS Number: 1314378-14-7
  • Molecular Formula: C30H36N2O10
  • Molecular Weight: 584.614
  • Catalog: Signaling Pathways PROTAC PROTAC Linker
  • Create Date: 2018-06-27 12:14:15
  • Modify Date: 2025-09-05 21:36:09
  • Fmoc-PEG4-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

Name 9H-Fluoren-9-ylmethyl {15-[(2,5-dioxo-1-pyrrolidinyl)oxy]-15-oxo-3,6,9,12-tetraoxapentadec-1-yl}carbamate
Synonyms Carbamic acid, N-[15-[(2,5-dioxo-1-pyrrolidinyl)oxy]-15-oxo-3,6,9,12-tetraoxapentadec-1-yl]-, 9H-fluoren-9-ylmethyl ester
9H-Fluoren-9-ylmethyl {15-[(2,5-dioxo-1-pyrrolidinyl)oxy]-15-oxo-3,6,9,12-tetraoxapentadec-1-yl}carbamate
Description Fmoc-PEG4-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

Alkyl/ether

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562.

Density 1.3±0.1 g/cm3
Molecular Formula C30H36N2O10
Molecular Weight 584.614
Exact Mass 584.237000
LogP 0.78
Index of Refraction 1.590
Storage condition -20°C
Hazard Codes Xi
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