BnO-PEG1-CH2CO2tBu

Modify Date: 2024-01-03 20:19:12

BnO-PEG1-CH2CO2tBu Structure
BnO-PEG1-CH2CO2tBu structure
Common Name BnO-PEG1-CH2CO2tBu
CAS Number 1309451-06-6 Molecular Weight 266.33300
Density N/A Boiling Point N/A
Molecular Formula C15H22O4 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of BnO-PEG1-CH2CO2tBu


BnO-PEG1-CH2CO2tBu is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

 Names

Name tert-butyl 2-(2-(benzyloxy)ethoxy)acetate
Synonym More Synonyms

 BnO-PEG1-CH2CO2tBu Biological Activity

Description BnO-PEG1-CH2CO2tBu is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

Alkyl/ether

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

 Chemical & Physical Properties

Molecular Formula C15H22O4
Molecular Weight 266.33300
Exact Mass 266.15200
PSA 44.76000
LogP 2.56150
Storage condition 2-8℃

 Precursor & DownStream

Precursor  0

DownStream  1

 Synonyms

MFCD28015768