157759-50-7
157759-50-7 structure
- Name: Bromo-PEG1-CH2-Boc
- Chemical Name: Bromo-PEG1-CH2CO2tBu
- CAS Number: 157759-50-7
- Molecular Formula: C8H15BrO3
- Molecular Weight: 239.107
- Catalog: Signaling Pathways PROTAC PROTAC Linker
- Create Date: 2018-06-16 21:43:09
- Modify Date: 2024-01-08 21:31:21
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Bromo-PEG1-CH2-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
| Name | Bromo-PEG1-CH2CO2tBu |
|---|---|
| Synonyms |
Acetic acid, 2-(2-bromoethoxy)-, 1,1-dimethylethyl ester
2-Methyl-2-propanyl (2-bromoethoxy)acetate MFCD28122952 |
| Description | Bromo-PEG1-CH2-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. |
|---|---|
| Related Catalog | |
| Target |
PEGs Alkyl/ether |
| In Vitro | PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1]. |
| References |
| Density | 1.3±0.1 g/cm3 |
|---|---|
| Boiling Point | 268.1±15.0 °C at 760 mmHg |
| Molecular Formula | C8H15BrO3 |
| Molecular Weight | 239.107 |
| Flash Point | 115.9±20.4 °C |
| Exact Mass | 238.020447 |
| LogP | 2.43 |
| Vapour Pressure | 0.0±0.5 mmHg at 25°C |
| Index of Refraction | 1.460 |