| Name | 2-[2-[2-[2-[2-(2-phenylmethoxyethoxy)ethoxy]ethoxy]ethoxy]ethoxy]ethanol |
|---|---|
| Synonyms |
1-Phenyl-2,5,8,11,14,17-hexaoxanonadecan-19-ol
2,5,8,11,14,17-Hexaoxanonadecan-19-ol, 1-phenyl- Hexaethylene Glycol Monobenzyl Ether 1-hydroxy-3,6,9,12,15,18-hexaoxa-19-phenyl-nonadecane 2-[2-[2-[2-[2-[2-(Benzyloxy)ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethanol |
| Description | BnO-PEG6-OH is a non-cleavable 6 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs). |
|---|---|
| Related Catalog | |
| Target |
Non-cleavable |
| In Vitro | ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker. |
| References |
| Density | 1.1±0.1 g/cm3 |
|---|---|
| Boiling Point | 473.6±40.0 °C at 760 mmHg |
| Molecular Formula | C19H32O7 |
| Molecular Weight | 372.453 |
| Flash Point | 240.3±27.3 °C |
| Exact Mass | 372.214813 |
| PSA | 75.61000 |
| LogP | -0.54 |
| Vapour Pressure | 0.0±1.2 mmHg at 25°C |
| Index of Refraction | 1.494 |
|
~71%
24342-68-5 |
| Literature: Gartiser, Thierry; Selve, Claude; Mansuy, Laurence; Robert, Alain; Delpuech, Jean-Jacques Journal of Chemical Research, Miniprint, 1984 , # 9 p. 2672 - 2691 |
|
~83%
24342-68-5 |
| Literature: Loiseau, Francois A.; Hii, King Kuok; Hill, Alison M. Journal of Organic Chemistry, 2004 , vol. 69, # 3 p. 639 - 647 |
|
~99%
24342-68-5 |
| Literature: Pilkington-Miksa, Michael A.; Sarkar, Supti; Writer, Michele J.; Barker, Susie E.; Shamlou, Parviz Ayazi; Hart, Stephen L.; Hailes, Helen C.; Tabor, Alethea B. European Journal of Organic Chemistry, 2008 , # 17 p. 2900 - 2914 |
|
~70%
24342-68-5 |
| Literature: Chen, Bin; Baumeister, Ute; Pelzl, Gerhard; Das, Malay Kumar; Zeng, Xiangbing; Ungar, Goran; Tschierske, Garsten Journal of the American Chemical Society, 2005 , vol. 127, # 47 p. 16578 - 16591 |
|
~19%
24342-68-5 |
| Literature: Glaxo Wellcome Inc. Patent: US6355646 B1, 2002 ; Location in patent: Page column 13 ; |
| Precursor 6 | |
|---|---|
| DownStream 1 | |