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1807537-31-0

1807537-31-0 structure
1807537-31-0 structure
  • Name: BnO-PEG5-Boc
  • Chemical Name: 2-Methyl-2-propanyl 1-phenyl-2,5,8,11,14,17-hexaoxanonadecan-19-oate
  • CAS Number: 1807537-31-0
  • Molecular Formula: C23H38O8
  • Molecular Weight: 442.543
  • Catalog: Signaling Pathways PROTAC PROTAC Linker
  • Create Date: 2018-06-05 21:50:54
  • Modify Date: 2024-01-08 22:43:34
  • BnO-PEG5-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

Name 2-Methyl-2-propanyl 1-phenyl-2,5,8,11,14,17-hexaoxanonadecan-19-oate
Synonyms MFCD28142466
2,5,8,11,14,17-Hexaoxanonadecan-19-oic acid, 1-phenyl-, 1,1-dimethylethyl ester
2-Methyl-2-propanyl 1-phenyl-2,5,8,11,14,17-hexaoxanonadecan-19-oate
Description BnO-PEG5-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

Density 1.1±0.1 g/cm3
Boiling Point 507.3±45.0 °C at 760 mmHg
Molecular Formula C23H38O8
Molecular Weight 442.543
Flash Point 214.4±28.8 °C
Exact Mass 442.256653
LogP 1.81
Vapour Pressure 0.0±1.3 mmHg at 25°C
Index of Refraction 1.483