Name | Tos-PEG2-CH2CO2tBu |
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Synonyms |
Acetic acid, 2-[2-[[(4-methylphenyl)sulfonyl]oxy]ethoxy]-, 1,1-dimethylethyl ester
2-Methyl-2-propanyl (2-{[(4-methylphenyl)sulfonyl]oxy}ethoxy)acetate MFCD28122953 |
Description | Tos-PEG1-CH2-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. |
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Related Catalog | |
Target |
PEGs Alkyl/ether |
In Vitro | PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1]. |
References |
Density | 1.2±0.1 g/cm3 |
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Boiling Point | 449.0±30.0 °C at 760 mmHg |
Molecular Formula | C15H22O6S |
Molecular Weight | 330.397 |
Flash Point | 225.4±24.6 °C |
Exact Mass | 330.113708 |
LogP | 2.93 |
Vapour Pressure | 0.0±1.1 mmHg at 25°C |
Index of Refraction | 1.503 |