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1309451-06-6

1309451-06-6 structure
1309451-06-6 structure
  • Name: BnO-PEG1-CH2CO2tBu
  • Chemical Name: tert-butyl 2-(2-(benzyloxy)ethoxy)acetate
  • CAS Number: 1309451-06-6
  • Molecular Formula: C15H22O4
  • Molecular Weight: 266.33300
  • Catalog: Signaling Pathways PROTAC PROTAC Linker
  • Create Date: 2016-01-21 05:55:03
  • Modify Date: 2024-01-03 20:19:12
  • BnO-PEG1-CH2CO2tBu is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

Name tert-butyl 2-(2-(benzyloxy)ethoxy)acetate
Synonyms MFCD28015768
Description BnO-PEG1-CH2CO2tBu is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

Alkyl/ether

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

Molecular Formula C15H22O4
Molecular Weight 266.33300
Exact Mass 266.15200
PSA 44.76000
LogP 2.56150
Storage condition 2-8℃
Precursor  0

DownStream  1