(R,S,S)-VH032

Modify Date: 2024-03-15 07:46:58

(R,S,S)-VH032 structure	Common Name	(R,S,S)-VH032
	CAS Number	2230826-33-0	Molecular Weight	430.56
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₂₂H₃₀N₄O₃S	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of (R,S,S)-VH032

(R,S,S)-VH032 is Ligand for E3 Ligase used in the synthesis of PROTACs. VH032 is a VHL ligand and VHL/HIF-1α interaction inhibitor that recruits von Hippel-Lindau (VHL) proteins. (R,S,S)-VH032 synthesizes the tau-targeting small molecule PROTAC C004019 (HY-138669)[1].

Name	(R,S,S)-VH032

Description	(R,S,S)-VH032 is Ligand for E3 Ligase used in the synthesis of PROTACs. VH032 is a VHL ligand and VHL/HIF-1α interaction inhibitor that recruits von Hippel-Lindau (VHL) proteins. (R,S,S)-VH032 synthesizes the tau-targeting small molecule PROTAC C004019 (HY-138669)[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> PROTAC >> Ligand for E3 Ligase
Target	VHL[1]
References	[1]. Wang W, et al. A novel small-molecule PROTAC selectively promotes tau clearance to improve cognitive functions in Alzheimer-like models. Theranostics. 2021 Mar 11;11(11):5279-5295.

Molecular Formula	C₂₂H₃₀N₄O₃S
Molecular Weight	430.56
Storage condition	2-8°C

Shanghai Nianxing Industrial Co., Ltd
China
Product Name: (R,S,S)-VH032
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Purity: 95.0%
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(R,S,S)-VH032

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