NH-bis-PEG3
Modify Date: 2025-08-21 10:26:36
NH-bis-PEG3 structure
|
Common Name | NH-bis-PEG3 | ||
|---|---|---|---|---|
| CAS Number | 25743-12-8 | Molecular Weight | 281.34600 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C12H27NO6 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of NH-bis-PEG3NH-bis-PEG3 is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. |
| Name | 2-[2-[2-[2-[2-(2-hydroxyethoxy)ethoxy]ethylamino]ethoxy]ethoxy]ethanol |
|---|---|
| Synonym | More Synonyms |
| Description | NH-bis-PEG3 is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. |
|---|---|
| Related Catalog | |
| Target |
PEGs |
| In Vitro | PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1]. |
| References |
| Molecular Formula | C12H27NO6 |
|---|---|
| Molecular Weight | 281.34600 |
| Exact Mass | 281.18400 |
| PSA | 89.41000 |
| InChIKey | JXAGXOHHOAQFIK-UHFFFAOYSA-N |
| SMILES | OCCOCCOCCNCCOCCOCCO |
|
~87%
NH-bis-PEG3 CAS#:25743-12-8 |
| Literature: Iqbal, Mudassir; Huskens, Jurriaan; Sypula, Michal; Modolo, Giuseppe; Verboom, Willem New Journal of Chemistry, 2011 , vol. 35, # 11 p. 2591 - 2600 |
|
~56%
NH-bis-PEG3 CAS#:25743-12-8 |
| Literature: Maeda, Hirokazu; Furuyoshi, Shigeo; Nakatsuji, Yohji; Okahara, Mitsuo Tetrahedron, 1982 , vol. 38, # 22 p. 3359 - 3362 |
|
~%
NH-bis-PEG3 CAS#:25743-12-8 |
| Literature: Iqbal, Mudassir; Huskens, Jurriaan; Sypula, Michal; Modolo, Giuseppe; Verboom, Willem New Journal of Chemistry, 2011 , vol. 35, # 11 p. 2591 - 2600 |
|
~%
NH-bis-PEG3 CAS#:25743-12-8 |
| Literature: Maeda, Hirokazu; Furuyoshi, Shigeo; Nakatsuji, Yohji; Okahara, Mitsuo Tetrahedron, 1982 , vol. 38, # 22 p. 3359 - 3362 |
![2-[2-(2-Aminoethoxy)ethoxy]ethanol structure](https://image.chemsrc.com/caspic/352/6338-55-2.png)
![2-(2-[2-(2-HYDROXY-ETHOXY)-ETHOXY]-ETHYL)-ISOINDOLE-1,3-DIONE structure](https://image.chemsrc.com/caspic/045/75001-08-0.png)
CAS#:33941-15-0| 3,6,12,15-Tetraoxa-9-azaheptadecane-1,17-diol |