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2055024-51-4

2055024-51-4 structure
2055024-51-4 structure
  • Name: NH-bis(PEG3-Boc)
  • Chemical Name: NH-bis(PEG3-C2-NH-Boc)
  • CAS Number: 2055024-51-4
  • Molecular Formula: C26H53N3O10
  • Molecular Weight: 567.71
  • Catalog: Signaling Pathways PROTAC PROTAC Linker
  • Create Date: 2020-06-01 11:10:44
  • Modify Date: 2024-01-09 20:38:24
  • NH-bis(PEG3-C2-NH-Boc) is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

Name NH-bis(PEG3-C2-NH-Boc)
Synonyms MFCD29918213
Description NH-bis(PEG3-C2-NH-Boc) is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

Alkyl/ether

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

Molecular Formula C26H53N3O10
Molecular Weight 567.71