NH-bis(PEG3-t-butyl ester)

Modify Date: 2024-01-12 15:23:33

NH-bis(PEG3-t-butyl ester) Structure
NH-bis(PEG3-t-butyl ester) structure
Common Name NH-bis(PEG3-t-butyl ester)
CAS Number 1814901-03-5 Molecular Weight 537.68
Density N/A Boiling Point N/A
Molecular Formula C26H51NO10 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of NH-bis(PEG3-t-butyl ester)


NH-bis(PEG3-Boc) is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

 Names

Name NH-bis(PEG3-Boc)
Synonym More Synonyms

 NH-bis(PEG3-t-butyl ester) Biological Activity

Description NH-bis(PEG3-Boc) is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

 Chemical & Physical Properties

Molecular Formula C26H51NO10
Molecular Weight 537.68

 Synonyms

MFCD29912753