Bis-PEG3-t-butyl ester

Modify Date: 2024-01-07 14:55:20

Bis-PEG3-t-butyl ester Structure
Bis-PEG3-t-butyl ester structure
Common Name Bis-PEG3-t-butyl ester
CAS Number 1611468-29-1 Molecular Weight 362.46
Density N/A Boiling Point N/A
Molecular Formula C18H34O7 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Bis-PEG3-t-butyl ester


Bis-PEG3-t-butyl ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

 Names

Name Bis-PEG3-t-butyl ester
Synonym More Synonyms

 Bis-PEG3-t-butyl ester Biological Activity

Description Bis-PEG3-t-butyl ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

 Chemical & Physical Properties

Molecular Formula C18H34O7
Molecular Weight 362.46

 Synonyms

MFCD29059859