Benzyloxy carbonyl-PEG3-t-butyl ester

Modify Date: 2024-01-16 08:41:44

Benzyloxy carbonyl-PEG3-t-butyl ester Structure
Benzyloxy carbonyl-PEG3-t-butyl ester structure
Common Name Benzyloxy carbonyl-PEG3-t-butyl ester
CAS Number 1835759-86-8 Molecular Weight 396.47
Density N/A Boiling Point N/A
Molecular Formula C21H32O7 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Benzyloxy carbonyl-PEG3-t-butyl ester


Benzyloxy carbonyl-PEG3-C2-Boc is an alkyl/ether-based PROTAC linker that can be used in the synthesis of PROTACs[1].

 Names

Name Benzyloxy carbonyl-PEG3-C2-Boc
Synonym More Synonyms

 Benzyloxy carbonyl-PEG3-t-butyl ester Biological Activity

Description Benzyloxy carbonyl-PEG3-C2-Boc is an alkyl/ether-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

Alkyl/ether

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

 Chemical & Physical Properties

Molecular Formula C21H32O7
Molecular Weight 396.47

 Synonyms

MFCD29042340