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1964503-36-3

1964503-36-3 structure
1964503-36-3 structure
  • Name: NH-bis(PEG2-t-butyl ester)
  • Chemical Name: NH-bis(PEG2-C2-Boc)
  • CAS Number: 1964503-36-3
  • Molecular Formula: C22H43NO8
  • Molecular Weight: 449.58
  • Catalog: Signaling Pathways PROTAC PROTAC Linker
  • Create Date: 2020-06-01 20:47:11
  • Modify Date: 2024-01-10 12:43:32
  • NH-bis(PEG2-C2-Boc) is an alkyl/ether-based PROTAC linker that can be used in the synthesis of PROTACs[1].

Name NH-bis(PEG2-C2-Boc)
Synonyms MFCD29912840
Description NH-bis(PEG2-C2-Boc) is an alkyl/ether-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

Alkyl/ether

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

Molecular Formula C22H43NO8
Molecular Weight 449.58