145916-41-2
145916-41-2 structure
- Name: Propargyl-PEG2-Tos
- Chemical Name: 2-(prop-2-yn-1-yloxy)ethyl 4-methylbenzenesulfonate
- CAS Number: 145916-41-2
- Molecular Formula: C12H14O4S
- Molecular Weight: 254.30200
- Catalog: Signaling Pathways PROTAC PROTAC Linker
- Create Date: 2016-12-26 15:16:36
- Modify Date: 2024-01-08 09:26:44
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Propargyl-PEG2-Tos is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
| Name | 2-(prop-2-yn-1-yloxy)ethyl 4-methylbenzenesulfonate |
|---|---|
| Synonyms |
2-(2-propynyloxy)ethanol p-toluenesulfonate
2-(propargyloxy)ethyl p-toluenesulfonate 3-oxohex-5-ynyl tosylate 2-(2-propynyloxy)ethyl tosylate 2-prop-2-ynyloxyethyl p-toluenesulfonate 2-(prop-2-ynyloxy)ethyl p-toluenesulfonate |
| Description | Propargyl-PEG2-Tos is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. |
|---|---|
| Related Catalog | |
| Target |
PEGs |
| In Vitro | PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1]. |
| References |
| Molecular Formula | C12H14O4S |
|---|---|
| Molecular Weight | 254.30200 |
| Exact Mass | 254.06100 |
| PSA | 60.98000 |
| LogP | 2.43090 |