PROTAC MDM2 Degrader-4

Modify Date: 2025-08-21 18:22:24

PROTAC MDM2 Degrader-4 Structure
PROTAC MDM2 Degrader-4 structure
Common Name PROTAC MDM2 Degrader-4
CAS Number 2249750-24-9 Molecular Weight 1393.19
Density N/A Boiling Point N/A
Molecular Formula C70H74Cl4N8O14 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of PROTAC MDM2 Degrader-4


PROTAC MDM2 Degrader-4 is a MDM2 degrader based on PROTAC technology. PROTAC MDM2 Degrader-4 composes of a potent MDM2 inhibitor, linker, and the MDM2 ligand for E3 ubiquitin ligase[1].

 Names

Name PROTAC MDM2 Degrader-4

 PROTAC MDM2 Degrader-4 Biological Activity

Description PROTAC MDM2 Degrader-4 is a MDM2 degrader based on PROTAC technology. PROTAC MDM2 Degrader-4 composes of a potent MDM2 inhibitor, linker, and the MDM2 ligand for E3 ubiquitin ligase[1].
Related Catalog
References

[1]. Method of inducing of self-degradation of MDM2 using E3 ubiquitin ligase dimer amide small molecule PROTACs. CN108610333A.

 Chemical & Physical Properties

Molecular Formula C70H74Cl4N8O14
Molecular Weight 1393.19
InChIKey QEEHXVDZCBZARJ-ADRSHWTGSA-N
SMILES COc1ccc(C2=NC(c3ccc(Cl)cc3)C(c3ccc(Cl)cc3)N2C(=O)N2CCN(CC(=O)OCCOCCOCCOC(=O)CN3CCN(C(=O)N4C(c5ccc(OC)cc5OC(C)C)=NC(c5ccc(Cl)cc5)C4c4ccc(Cl)cc4)CC3=O)C(=O)C2)c(OC(C)C)c1
Storage condition 2-8°C
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