2361114-15-8
2361114-15-8 structure
- Name: PROTAC ER Degrader-4
- Chemical Name: PROTAC ER Degrader-4
- CAS Number: 2361114-15-8
- Molecular Formula: C53H67F3N6O8S
- Molecular Weight: 1005.19
- Catalog: Signaling Pathways PROTAC PROTAC
- Create Date: 2020-01-23 10:53:51
- Modify Date: 2024-01-10 18:48:26
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PROTAC ER Degrader-4 is a PROATC estrogen receptor (ER) degrader, binding to ER with an IC50 of 0.8 nM. PROTAC ER Degrader-4 induces ER degradation in MCF-7 cells with an IC50 of 0.3 nM[1].
| Name | PROTAC ER Degrader-4 |
|---|
| Description | PROTAC ER Degrader-4 is a PROATC estrogen receptor (ER) degrader, binding to ER with an IC50 of 0.8 nM. PROTAC ER Degrader-4 induces ER degradation in MCF-7 cells with an IC50 of 0.3 nM[1]. |
|---|---|
| Related Catalog | |
| Target |
VHL ER |
| In Vitro | PROTAC ER Degrader-4 shows equal to 100% ER degradation at 0.3 μM in the MCF-7 ER degradation cellular assay[1]. |
| References |
[1]. Bin Yang, et al. Compounds and their use in treating cancer. WO2019123367A1. |
| Molecular Formula | C53H67F3N6O8S |
|---|---|
| Molecular Weight | 1005.19 |
| Storage condition | 2-8°C |