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2454216-21-6

2454216-21-6 structure
2454216-21-6 structure
  • Name: Mal-PEG5-C2-NH2 hydrochloride
  • Chemical Name: Mal-PEG5-C2-NH2 hydrochloride
  • CAS Number: 2454216-21-6
  • Molecular Formula: C16H29ClN2O7
  • Molecular Weight: 396.86
  • Catalog: Signaling Pathways PROTAC PROTAC Linker
  • Create Date: 2021-09-05 18:00:21
  • Modify Date: 2024-01-09 00:14:51
  • Mal-PEG5-C2-NH2 hydrochloride is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

Name Mal-PEG5-C2-NH2 hydrochloride
Description Mal-PEG5-C2-NH2 hydrochloride is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

Molecular Formula C16H29ClN2O7
Molecular Weight 396.86