Mal-PEG5-C2-NH2 hydrochloride

Modify Date: 2024-01-09 00:14:51

Mal-PEG5-C2-NH2 hydrochloride Structure
Mal-PEG5-C2-NH2 hydrochloride structure
Common Name Mal-PEG5-C2-NH2 hydrochloride
CAS Number 2454216-21-6 Molecular Weight 396.86
Density N/A Boiling Point N/A
Molecular Formula C16H29ClN2O7 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Mal-PEG5-C2-NH2 hydrochloride


Mal-PEG5-C2-NH2 hydrochloride is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

 Names

Name Mal-PEG5-C2-NH2 hydrochloride

 Mal-PEG5-C2-NH2 hydrochloride Biological Activity

Description Mal-PEG5-C2-NH2 hydrochloride is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

 Chemical & Physical Properties

Molecular Formula C16H29ClN2O7
Molecular Weight 396.86