2305369-00-8

2305369-00-8 structure

Name: Pomalidomide-C2-NH2 hydrochloride
Chemical Name: E3 ligase Ligand 17 hydrochloride
CAS Number: 2305369-00-8
Molecular Formula: C₁₅H₁₇ClN₄O₄
Molecular Weight: 352.77
Catalog: Signaling Pathways PROTAC E3 Ligase Ligand-Linker Conjugate
Create Date: 2019-10-08 12:14:52
Modify Date: 2025-08-27 10:59:42
E3 ligase Ligand 17 hydrochloride is a ligand for E3 ubiquitin ligase. E3 ligase Ligand 17 hydrochloride can be connected to the ligand for protein by a linker to form PROTACs. PROTACs are inducers of ubiquitination-mediated degradation of cancer-promoting proteins[1].

Name	E3 ligase Ligand 17 hydrochloride

Description	E3 ligase Ligand 17 hydrochloride is a ligand for E3 ubiquitin ligase. E3 ligase Ligand 17 hydrochloride can be connected to the ligand for protein by a linker to form PROTACs. PROTACs are inducers of ubiquitination-mediated degradation of cancer-promoting proteins[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> PROTAC >> E3 Ligase Ligand-Linker Conjugate
Target	Cereblon
References	[1]. Shibata N, et al. Development of Protein Degradation Inducers of Androgen Receptor by Conjugation of Androgen Receptor Ligands and Inhibitor of Apoptosis Protein Ligands. J Med Chem. 2018 Jan 25;61(2):543-575.

Molecular Formula	C₁₅H₁₇ClN₄O₄
Molecular Weight	352.77