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2093152-79-3

2093152-79-3 structure
2093152-79-3 structure
  • Name: N-(Azido-PEG4)-N-bis(PEG4-t-butyl ester)
  • Chemical Name: N-(Azido-PEG4)-N-bis(PEG4-t-butyl ester)
  • CAS Number: 2093152-79-3
  • Molecular Formula: C40H78N4O16
  • Molecular Weight: 871.06
  • Catalog: Signaling Pathways PROTAC PROTAC Linker
  • Create Date: 2020-06-01 19:57:52
  • Modify Date: 2024-01-07 12:33:15
  • N-(Azido-PEG4)-N-bis(PEG4-t-butyl ester) is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

Name N-(Azido-PEG4)-N-bis(PEG4-t-butyl ester)
Description N-(Azido-PEG4)-N-bis(PEG4-t-butyl ester) is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

Alkyl/ether

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

Molecular Formula C40H78N4O16
Molecular Weight 871.06
Hazard Codes Xi