2-(Azido-PEG3-amido)-1,3-bis(NHS ester) is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Lenalidomide-PEG1-azide is a E3 ligase lgand-linker conjugate. Lenalidomide-PEG1-azide incorporates the Lenalidomide based cereblon ligand and a linker. Lenalidomide-PEG1-azide can be used to design a PROTAC BRD4 Degrader-2 (HY-133136)[1].
Pomalidomide-PEG1-NH2 hydrochloride is a synthesized E3 ligase ligand-linker conjugate that incorporates the Pomalidomide based cereblon ligand and 1-unit PEG linker used in PROTAC technology[1].
Thalidomide-4-C3-NH2 hydrochloride is the Thalidomide-based cereblon ligand used in the recruitment of CRBN protein. Thalidomide-4-C3-NH2 hydrochloride can be connected to the ligand for protein by a linker to form PROTACs[1].
THP-PEG1-alcohol is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Carboxy-PEG4-phosphonic acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Amino-PEG3-C2-sulfonic acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
APN-C3-NH-Boc is an alkyl/ether-based PROTAC linker that can be used in the synthesis of PROTACs[1].
N-(Amino-PEG1)-N-bis(PEG2-propargyl) is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
DBCO-PEG9-DBCO is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Thalidomide-O-C2-acid is a synthesized E3 ligase ligand-linker conjugate that incorporates the Thalidomide based cereblon ligand and a linker used in PROTAC technology[1].
Benzyl-PEG2-ethanol is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Mal-PEG8-alcohol is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
THAL-SNS-032 is a selective CDK9 degrader PROTAC consisting of a CDK-binding SNS-032 ligand linked to a thalidomide derivative that binds the E3 ubiquitin ligase Cereblon (CRBN)[1].
Boc-NH-PEG5-azide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
m-PEG4-Boc is a cleavable 4 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1]. m-PEG4-Boc is also a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[2].
2-Amino-13-bis(carboxylethoxy)propane is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
1-Isothiocyanato-PEG3-azide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Azide-PEG3-C1-Ala is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
TAMRA-PEG4-methyltetrazine is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Propargyl-PEG4-S-PEG4-acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Aminooxy-PEG3-acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Methyltetrazine-propylamine is an alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Acid-PEG6-C2-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
MS21, a novel degrader of AKT, selectively inhibits the growth of PI3K/PTEN pathway-mutant cancers with wild-type KRAS and BRAF.
Mal-PEG2-PFP ester is a Alkyl/ether-based PROTAC linker can be used in the synthesis of PROTACs.
m-PEG8-ethoxycarbonyl--NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
PC-PEG11-Azide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
m-PEG1-NHS ester is a PEG/Alkyl/ether-based PROTAC linker can be used in the synthesis of PROTACs.
N-(Amino-PEG4)-N-bis(PEG4-Boc) is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].